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2022-05-06-hemoptysis.md (1256B)


      1 # hemoptysis
      2 
      3 Scott McCall
      4 
      5 
      6 ## when to intubate
      7 
      8 if they've already coded, or are very close to it
      9 
     10 if a person is awake enough to cough, 
     11 they are better at clearing the small airways than we are with suction
     12 
     13 
     14 ## ABCs
     15 
     16 A - late intubation
     17 A - mainstem/positioning (intubate the clear side, put the sick side down)
     18 
     19 B - 
     20 
     21 C - ~3L of blood can fit in a typical lung, may need massive transfusion protocol
     22 
     23 
     24 ## meds
     25 
     26 TXA - if the inhaled drug can get to the problematic areas, e.g. bronchitis/bronchiectasis
     27   - literature suggests TXA is helpful if the coagulation cascade is relatively normal (e.g. no mortality benefit in cirrhosis)
     28 
     29 PCC vs FFP - 
     30 no in vivo or in vitro evidence that 
     31 drug levels or coagulation parameters are meaningfully improved with PCC, 
     32 Xa decoy (Andexanet Alfa) does work but is expensive and not often stocked
     33 
     34 Cryo
     35 
     36 
     37 ## imaging
     38 
     39 CT bronchial artery protocol (CT angio w relatively early shots)
     40 
     41 GGO, can be tree-in-bud (clot)
     42 
     43 ## causes
     44 
     45 - bronchitis/bronchiectasis (in bronchiectasis the vessels are closer to the surface)
     46 - PNA
     47 - PE (usu late, distal, scant, r/t necrosis)
     48 - malignancy - things that recruit VEG-F - thymic, thyroid (papillary), melanoma, Kaposi
     49 - cavitary lung lesions (TB, fungal balls, Erasmus formation)