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commit bd8e5b98dc04c667ab0e4a80a7d3ac8273fb8696
parent dce1764eb82ec253727099c022e6890fd6054609
Author: Beau <cbeauhilton@gmail.com>
Date:   Fri, 29 Mar 2024 14:47:29 -0500

update

Diffstat:
Msite/posts/s1.md | 6++++++
1 file changed, 6 insertions(+), 0 deletions(-)

diff --git a/site/posts/s1.md b/site/posts/s1.md @@ -137,10 +137,16 @@ but aren't fully captured in the other metrics. Though hand-foot syndrome is not a lethal problem, it can be a huge quality-of-life problem, particularly when the point of therapy is palliative in the first place. + The same group also published a [retrospective](https://doi.org/10.1080/0284186X.2016.1278459) on 52 patients who had serious hand-foot syndrome on capecitabine and were switched to S1, which they then tolerated beautifully. +Every patient started on capecitabine, +and was switched to S1 due to hand-foot syndrome. +The graph below is from this paper. +"Before" is on the left, and "after" is on the right. +The difference is stark. ![HFS improves significantly after switching from capecitabine to S1](/images/s1-cape-hfs.jpg)