commit bd8e5b98dc04c667ab0e4a80a7d3ac8273fb8696
parent dce1764eb82ec253727099c022e6890fd6054609
Author: Beau <cbeauhilton@gmail.com>
Date: Fri, 29 Mar 2024 14:47:29 -0500
update
Diffstat:
1 file changed, 6 insertions(+), 0 deletions(-)
diff --git a/site/posts/s1.md b/site/posts/s1.md
@@ -137,10 +137,16 @@ but aren't fully captured in the other metrics.
Though hand-foot syndrome is not a lethal problem,
it can be a huge quality-of-life problem,
particularly when the point of therapy is palliative in the first place.
+
The same group also published a [retrospective](https://doi.org/10.1080/0284186X.2016.1278459)
on 52 patients
who had serious hand-foot syndrome on capecitabine
and were switched to S1, which they then tolerated beautifully.
+Every patient started on capecitabine,
+and was switched to S1 due to hand-foot syndrome.
+The graph below is from this paper.
+"Before" is on the left, and "after" is on the right.
+The difference is stark.
![HFS improves significantly after switching from capecitabine to S1](/images/s1-cape-hfs.jpg)