commit 733d7d3f7f9282014183a0fe07e1ebf3de449d2a
parent a1126f834b6cc8ae238947a61bdfd9414af027f1
Author: C. Beau Hilton <cbeauhilton@gmail.com>
Date: Thu, 2 Jul 2020 13:06:29 -0500
memex update
Diffstat:
2 files changed, 31 insertions(+), 0 deletions(-)
diff --git a/index.md b/index.md
@@ -75,6 +75,8 @@ Vannevar Bush coined the term "memex" for a system of extending or indexing one'
## lectures
### 2019
- [dr rose on ai in healthcare](learn/dr_rose_on_ai_in_healthcare.md)
+### 2020
+- [2020-07-02-noon-conference](learn/2020-07-02-noon-conference.md)
## blogs
diff --git a/learn/2020-07-02-noon-conference.md b/learn/2020-07-02-noon-conference.md
@@ -0,0 +1,29 @@
+# Case 1: New, acute onset ascites and abdominal pain
+
+Portal vein thrombosis often does *not* have remarkable LFT changes.
+
+Triple-phase CT - indicated when?
+
+Malignant culture-negative neutrocytic ascites - case reports in 2017 and 2019, no clear guidance for management
+
+# Case 2:
+
+beta-D-glucan - invasive fungal infx test, takes time to result (how long? how good?)
+
+GMS stain - identifies many kinds of fungi, pathologists mostly report morphology with possibilities that require clinical correlation <https://cmr.asm.org/content/24/2/247>
+
+## pneumocystis jirovecii pneumonia in non-HIV infx pts
+
+Stem cell tx, solid organ tx, heme malignancies, high-dose steroids, immunosuppression
+
+Risk for solid organ tx depends on tx, ?mostly d/t degree of immunosuppression
+
+Presents with nonspecific sx: dysnpea, fever, dry cough, hypoxia out of proportion to level of distress (this last point a personal obs from presenter - mb worth a study!)
+
+Definitive dx with GMS from sputum or BAL, direct fluorescent antibody, PCR (PCR may have higher diagnostic yield)
+
+Presumptive dx (may be too hypoxic for bronchoscopy): increased beta-D-glucan, radiographic findings, clinical features, possibly increased LDH, and r/o other fungal causes
+
+Firstline tx: TMP-SMX 15-20mg/kg, desensitize if minor allergy+steroids if severe (low PaO2 or requiring supplemental O2)
+
+Secondline tx: clindamycin+primaquine; clindamycin+primaquine or TMP + dapsone if moderate; 21 total days.
