commit dba51a0fffcddf06196a5fecfd395ccf85e3b1b6
parent 77a8ff39ddee77276c317e200bd3cc74576829be
Author: C. Beau Hilton <cbeauhilton@gmail.com>
Date: Thu, 27 Aug 2020 09:16:20 -0500
memex update
Diffstat:
1 file changed, 3 insertions(+), 3 deletions(-)
diff --git a/learn/2020-08-27-grand-rounds.md b/learn/2020-08-27-grand-rounds.md
@@ -23,12 +23,12 @@ Controversy: Nucleic acid amplification tests (NAAT) cannot distinguish coloniza
Controversy: should we use the most sensitive test (NAAT) to find even colonization, to control spread?
Or use toxin tests up front, to catch the cases severe enough to produce detectable toxin? (i.e. use a purposefully less sensitive test that is possibly more specific for more severe dz)
-Classifying severe/complicated CDI:
+Classifying severe/complicated CDI
- Severe: WBC >15k, Cr >1.5x normal, absolute serum Cr >1.5 if no baseline available
- Fulminant: hypotn, shock, ileus, toxi megacolon
- Recurrent: 2-8wks from last positive specimen OR clinical response
-Studying microbiome:
+Studying microbiome
- Anatomy
- structure: "who is there?"
- Physiology:
@@ -65,6 +65,6 @@ YES.
Wiens now doing prospective work - YES again.
-Next steps:
+Next steps
- moving from association to causation
- precision medicine that includes host genome and microbiota genomes, etc.
